The One Health Commission (OHC) believes that One Health ‘can’ become the default way of doing business at all levels of academia, research, government, policy and industry when individuals and groups from around the world work together in organized team efforts. In keeping with its mission, vision and goals, the OHC identifies gaps where implementation of One Health thinking and acting could have a powerful positive impact, saving lives, both animal and human, and improving ecosystem health for all living creatures. Individuals and groups from around the world are urged to join hands and work together in trans-disciplinary volunteer team efforts.The OHC provides a platform and opportunities for individuals to actively participate in the global One Health movement when they may not otherwise have avenues in which to act.